HSPMdb Accession NoHSPMDB000203
PMID15448148
TargetHsp70
HSP NameSsa1p and TAg /ydj1P
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (TAg stimulated)
Compound NameNSC-630668-R/1
IUPAC Name6-[5-(ethoxycarbonylcarbamoyl)-2,4-dioxopyrimidin-1-yl]hexyl N-[6-[6-[5-(ethoxycarbonylcarbamoyl)-2,4-dioxopyrimidin-1-yl]hexoxycarbonylamino]hexyl]carbamate
SMILESCCOC(=O)NC(=O)C1=CN(C(=O)NC1=O)CCCCCCOC(=O)NCCCCCCNC(=O)OCCCCCCN2C=C(C(=O)NC2=O)C(=O)NC(=O)OCC
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -1.5 (at 0.3 mM)
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000203

NSC-630668-R/1

Physicochemical Properties