HSPMdb Accession NoHSPMDB000148
PMID15448148
TargetHsp70
HSP NameSsa1p
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity (endogenous)
Compound Name624392
IUPAC Nameethyl N-[1-[2-[6-[[2-[5-(ethoxycarbonylcarbamoyl)-2,4-dioxopyrimidin-1-yl]ethyl-(2-hydroxyethyl)carbamoyl]amino]hexylcarbamoyl-(2-hydroxyethyl)amino]ethyl]-2,4-dioxopyrimidine-5-carbonyl]carbamate
SMILESCCOC(=O)NC(=O)C1=CN(C(=O)NC1=O)CCN(CCO)C(=O)NCCCCCCNC(=O)N(CCN2C=C(C(=O)NC2=O)C(=O)NC(=O)OCC)CCO
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold ChangeFold change -1.3 (at 0.3 mM)
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000148

624392

Physicochemical Properties