| HSPMdb Accession No | HSPMDB000130 |
| PMID | 18191466 |
| Target | Hsp70 |
| HSP Name | DnaK/DnaJ/GrpE |
| Organism | Bacteria |
| Localization | Cytosol and membrane |
| Enzymatic activity | Inhibition of chaperone activity |
| Compound Name | 116-8e |
| IUPAC Name | benzyl 4-{[1,1'-biphenyl]-4-yl}-1-{5-[({[1,1'-biphenyl]-4-yl}(butylcarbamoyl)methyl)(hexyl)carbamoyl]pentyl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| SMILES | CCCCCCN(C(C(=O)NCCCC)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)CCCCCN1C(=O)NC(C2=CC=C(C=C2)C2=CC=CC=C2)C(C(=O)OCC2=CC=CC=C2)=C1C |
| Class | Dihydropyrimidine derivative |
| EC50 (µM) | 30.4 |
| Type of Enzymatic Assay | Refolding assay (luciferase) |
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