HSPMdb Accession No | HSPMDB000129 |
PMID | 18191466 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ/GrpE |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | SW03 |
IUPAC Name | 3-[(3R)-3-[(3S)-3-{4-[4-(4-bromophenyl)-5-(ethoxycarbonyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]butanamido}-5-methylhexanamido]-3-phenylpropanamido]propanoic acid |
SMILES | CCOC(=O)C1=C(C)N(CCCC(=O)N[C@@H](CC(C)C)CC(=O)N[C@H](CC(=O)NCCC(O)=O)C2=CC=CC=C2)C(=O)NC1C1=CC=C(Br)C=C1 |
Class | Dihydropyrimidine derivative |
EC50 (µM) | 11 |
Type of Enzymatic Assay | Refolding assay (luciferase) |