HSPMdb Accession No | HSPMDB000127 |
PMID | 18191466 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ/GrpE |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 116-4d |
IUPAC Name | N-hydroxy-4-[5-(methoxycarbonyl)-2-oxo-6-(2-phenylethyl)-1,2,3,4-tetrahydropyrimidin-4-yl]-N-oxoanilinium |
SMILES | COC(=O)C1=C(CCC2=CC=CC=C2)NC(=O)NC1C1=CC=C(C=C1)[N+](O)=O |
Class | Dihydropyrimidine derivative |
EC50 (µM) | 8.8 |
Type of Enzymatic Assay | Refolding assay (luciferase) |