HSPMdb Accession No | HSPMDB000114 |
PMID | 29414793 |
Target | Hsp70 |
HSP Name | Hsp72/DnaJ2/BAG2 |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | IT2-144 |
IUPAC Name | N-(2,5-difluorophenyl)-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine |
SMILES | CC1=C(N2C=CC=CC2=N1)C1=CSC(NC2=CC(F)=CC=C2F)=N1 |
Class | 2-aminothiazoles derivative |
EC50 (µM) | 2.7 |
Cellular assay | MTT viability assay |
Cellular Model | MDA-MB-231 |
Disease | Cancer |