HSPMdb Accession No | HSPMDB000110 |
PMID | 29414793 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ/GrpE |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity (protein-protein interaction) |
Compound Name | IT2-171 |
IUPAC Name | N-benzyl-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine |
SMILES | CC1=C(N2C=CC=CC2=N1)C1=CSC(NCC2=CC=CC=C2)=N1 |
Class | 2-aminothiazoles derivative |
EC50 (µM) | >25 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |