| HSPMdb Accession No | HSPMDB000104 |
| PMID | 29414793 |
| Target | Hsp70 |
| HSP Name | DnaK/DnaJ/GrpE |
| Organism | Bacteria |
| Localization | Cytosol and membrane |
| Enzymatic activity | Inhibition of ATPase activity (protein-protein interaction) |
| Compound Name | IT2-149 |
| IUPAC Name | N-(2-fluoro-5-methylphenyl)-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine |
| SMILES | CC1=C(N2C=CC=CC2=N1)C1=CSC(NC2=CC(C)=CC=C2F)=N1 |
| Class | 2-aminothiazoles derivative |
| EC50 (µM) | >25 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Type of Enzymatic Assay | ATPase assay |
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