| HSPMdb Accession No | HSPMDB000102 |
| PMID | 29414793 |
| Target | Hsp70 |
| HSP Name | Hsp72/DnaJ2/BAG2 |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Enzymatic activity | Inhibition of ATPase activity (protein-protein interaction) |
| Compound Name | R |
| IUPAC Name | N-(5-chloro-2-methoxyphenyl)-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine |
| SMILES | COC1=CC=C(Cl)C=C1NC1=NC(=CS1)C1=C(C)N=C2C=CC=CN12 |
| Class | 2-aminothiazole derivative |
| EC50 (µM) | 9.5 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Type of Enzymatic Assay | ATPase assay |
Loading Please Wait ...