HSPMdb Accession NoHSPMDB000090
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name407
IUPAC NameN-(1-(3-cyclohexylthioureido)-3-methylbutyl)cinnamamide
SMILESCC(C)CC(NC(=O)C=Cc1ccccc1)NC(=S)NC2CCCCC2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition19.8 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT/LapR1.0
DiseaseCancer

Structure



HSPMDB000090

407

Physicochemical Properties