HSPMdb Accession NoHSPMDB000083
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name395
IUPAC NameN-(3-methyl-1-(3-o-tolylthioureido)butyl)cinnamamide
SMILESCC(C)CC(NC(=O)C=Cc1ccccc1)NC(=S)Nc2ccccc2C
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition12.8 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT/LapR1.0
DiseaseCancer

Structure



HSPMDB000083

395

Physicochemical Properties