HSPMdb Accession No | HSPMDB000082 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 394 |
IUPAC Name | N-(3,3-dimethyl-1-(3-o-tolylthioureido)butyl)cinnamamide |
SMILES | Cc1ccccc1NC(=S)NC(CC(C)(C)C)NC(=O)C=Cc2ccccc2 |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 18.9 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT/LapR1.0 |
Disease | Cancer |