HSPMdb Accession NoHSPMDB000079
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name391
IUPAC Name(E)-N-(3-methyl-1-(3-methylthioureido)butyl)-3-(3,4,5-trimethoxy-phenyl)acrylamide
SMILESCNC(=S)NC(CC(C)C)NC(=O)\C=C\c1cc(OC)c(OC)c(OC)c1
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition13 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT/LapR1.0
DiseaseCancer

Structure



HSPMDB000079

391

Physicochemical Properties