HSPMdb Accession No | HSPMDB000079 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 391 |
IUPAC Name | (E)-N-(3-methyl-1-(3-methylthioureido)butyl)-3-(3,4,5-trimethoxy-phenyl)acrylamide |
SMILES | CNC(=S)NC(CC(C)C)NC(=O)\C=C\c1cc(OC)c(OC)c(OC)c1 |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 13 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT/LapR1.0 |
Disease | Cancer |