HSPMdb Accession NoHSPMDB000075
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name387
IUPAC NameN-(3,3-dimethyl-1-(3-phenylthioureido)butyl)cinnamamide
SMILESCC(C)(C)CC(NC(=O)C=Cc1ccccc1)NC(=S)Nc2ccccc2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition34.6 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT/LapR1.0
DiseaseCancer

Structure



HSPMDB000075

387

Physicochemical Properties