HSPMdb Accession NoHSPMDB000073
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name384
IUPAC NameN-(cyclopropyl(3-pyridin-2-ylthioureido)methyl)cinnamamide
SMILESO=C(NC(NC(=S)Nc1ccccn1)C2CC2)C=Cc3ccccc3
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition6 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT/LapR1.0
DiseaseCancer

Structure



HSPMDB000073

384

Physicochemical Properties