HSPMdb Accession No | HSPMDB000059 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 409 |
IUPAC Name | N-(1-(3-cyclohexylthioureido)-2,2-dimethylpropyl)cinnamamide |
SMILES | CC(C)(C)C(NC(=O)C=Cc1ccccc1)NC(=S)NC2CCCCC2 |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 13 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT474 |
Disease | Cancer |