HSPMdb Accession NoHSPMDB000059
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name409
IUPAC NameN-(1-(3-cyclohexylthioureido)-2,2-dimethylpropyl)cinnamamide
SMILESCC(C)(C)C(NC(=O)C=Cc1ccccc1)NC(=S)NC2CCCCC2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition13 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000059

409

Physicochemical Properties