HSPMdb Accession NoHSPMDB000058
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name408
IUPAC NameN-(1-(3-cyclohexylthioureido)-2-methylpropyl)cinnamamide
SMILESCC(C)C(NC(=O)C=Cc1ccccc1)NC(=S)NC2CCCCC2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition10.3 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000058

408

Physicochemical Properties