HSPMdb Accession No | HSPMDB000056 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 406 |
IUPAC Name | (E)-N-(1-(3-cyclohexylthioureido)-2-methylpropyl)-3-(3,4,5-trimethoxyphenyl)acrylamide |
SMILES | COc1cc(/C=C/C(=O)NC(NC(=S)NC2CCCCC2)C(C)C)cc(OC)c1OC |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 15.3 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT474 |
Disease | Cancer |