HSPMdb Accession NoHSPMDB000052
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name397
IUPAC NameN-(cyclopropyl(3-o-tolylthioureido)methyl)cinnamamide
SMILESCc1ccccc1NC(=S)NC(NC(=O)C=Cc2ccccc2)C3CC3
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition6 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000052

397

Physicochemical Properties