HSPMdb Accession NoHSPMDB000051
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name396
IUPAC NameN-(2,2-dimethyl-1-(3-o-tolylthioureido)propyl)cinnamamide
SMILESCc1ccccc1NC(=S)NC(NC(=O)C=Cc2ccccc2)C(C)(C)C
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition7 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000051

396

Physicochemical Properties