HSPMdb Accession NoHSPMDB000049
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name394
IUPAC NameN-(3,3-dimethyl-1-(3-o-tolylthioureido)butyl)cinnamamide
SMILESCc1ccccc1NC(=S)NC(CC(C)(C)C)NC(=O)C=Cc2ccccc2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition18.2 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000049

394

Physicochemical Properties