HSPMdb Accession NoHSPMDB000044
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name389
IUPAC NameN-(cyclopropyl(3-phenylthioureido)methyl)cinnamamide
SMILESO=C(NC(NC(=S)Nc1ccccc1)C2CC2)C=Cc3ccccc3
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition3.8 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000044

389

Physicochemical Properties