HSPMdb Accession NoHSPMDB000043
PMID27155465
TargetHsp70
HSP NameHsp70-2
OrganismHuman
LocalizationCytosol and cytoskeleton
Cellular activityAntiproliferative activity
Compound Name388
IUPAC NameN-(2,2-dimethyl-1-(3-phenylthioureido)propyl)cinnamamide
SMILESCC(C)(C)C(NC(=O)C=Cc1ccccc1)NC(=S)Nc2ccccc2
ClassN,N'-disubstituted thiourea derivative
Site of InteractionNucleotide binding domain
Percentage Cell Growth Inhibition9.6 at 10 uM
Cellular assayLuminescence based viability assay
Cellular ModelBT474
DiseaseCancer

Structure



HSPMDB000043

388

Physicochemical Properties