HSPMdb Accession No | HSPMDB000042 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 387 |
IUPAC Name | N-(3,3-dimethyl-1-(3-phenylthioureido)butyl)cinnamamide |
SMILES | CC(C)(C)CC(NC(=O)C=Cc1ccccc1)NC(=S)Nc2ccccc2 |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 11.3 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT474 |
Disease | Cancer |