HSPMdb Accession No | HSPMDB000029 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | Hsp70-2 |
Organism | Human |
Localization | Cytosol and cytoskeleton |
Cellular activity | Antiproliferative activity |
Compound Name | 372 |
IUPAC Name | (E)-N-(2,2-dimethyl-1-(3-phenylthioureido)propyl)-3-(3,4,5-trimethoxyphenyl) acrylamide |
SMILES | COc1cc(/C=C/C(=O)NC(NC(=S)Nc2ccccc2)C(C)(C)C)cc(OC)c1OC |
Class | N,N'-disubstituted thiourea derivative |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 2.2 at 10 uM |
Cellular assay | Luminescence based viability assay |
Cellular Model | BT474 |
Disease | Cancer |