HSPMdb Accession NoHSPMDB000025
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name405
IUPAC Name(E)-N-(1-(3-cyclohexylthioureido)-2,2-dimethylpropyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
SMILESCOc1cc(/C=C/C(=O)NC(NC(=S)NC2CCCCC2)C(C)(C)C)cc(OC)c1OC
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change35.78% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000025

405

Physicochemical Properties