HSPMdb Accession No | HSPMDB000024 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 404 |
IUPAC Name | (E)-N-(1-(3-cyclohexylthioureido)-3-methylbutyl)-3-(3,4,5-trimethoxyphenyl)acrylamide |
SMILES | COc1cc(/C=C/C(=O)NC(CC(C)C)NC(=S)NC2CCCCC2)cc(OC)c1OC |
Class | N,N'-disubstituted thiourea derivative |
% Enzymatic Inhibition/Fold Change | 46.23% (at 200 uM) |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |