HSPMdb Accession NoHSPMDB000023
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name397
IUPAC NameN-(cyclopropyl(3-o-tolylthioureido)methyl)cinnamamide
SMILESCc1ccccc1NC(=S)NC(NC(=O)C=Cc2ccccc2)C3CC3
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change65.36% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000023

397

Physicochemical Properties