HSPMdb Accession NoHSPMDB000022
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name394
IUPAC NameN-(3,3-dimethyl-1-(3-o-tolylthioureido)butyl)cinnamamide
SMILESCc1ccccc1NC(=S)NC(CC(C)(C)C)NC(=O)C=Cc2ccccc2
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change40.95% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000022

394

Physicochemical Properties