HSPMdb Accession NoHSPMDB000021
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name392
IUPAC Name(E)-N-(2,2-dimethyl-1-(3-o-tolylthioureido)propyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
SMILESCOc1cc(/C=C/C(=O)NC(NC(=S)Nc2ccccc2C)C(C)(C)C)cc(OC)c1OC
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change50.5% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000021

392

Physicochemical Properties