HSPMdb Accession NoHSPMDB000020
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name380
IUPAC Name(E)-N-(3,3-dimethyl-1-(3-pyridin-3-ylthioureido)butyl)-3-(3,4,5-trimethoxyphenyl)acrylamide
SMILESCOc1cc(/C=C/C(=O)NC(CC(C)(C)C)NC(=S)Nc2cccnc2)cc(OC)c1OC
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change47.13% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000020

380

Physicochemical Properties