HSPMdb Accession NoHSPMDB000018
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name374
IUPAC Name(E)-N-(cyclopropyl(3-phenylthioureido)methyl)-3-(3,4,5-trimethoxy-phenyl)acrylamide
SMILESCOc1cc(/C=C/C(=O)NC(NC(=S)Nc2ccccc2)C3CC3)cc(OC)c1OC
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change50.45% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000018

374

Physicochemical Properties