HSPMdb Accession No | HSPMDB000017 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 371 |
IUPAC Name | (E)-N-(3-methyl-1-(3-pyridin-3-ylthioureido)butyl)-3-(3,4,5-trimethoxyphenyl) acrylamide |
SMILES | COc1cc(/C=C/C(=O)NC(CC(C)C)NC(=S)Nc2cccnc2)cc(OC)c1OC |
Class | N,N'-disubstituted thiourea derivative |
% Enzymatic Inhibition/Fold Change | 38.46% (at 200 uM) |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |