HSPMdb Accession NoHSPMDB000016
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name370
IUPAC Name(E)-N-(3-methyl-1-(3-phenylthioureido)butyl)-3-(3,4,5-trimethoxyphenyl) acrylamide
SMILESCOc1cc(/C=C/C(=O)NC(CC(C)C)NC(=S)Nc2ccccc2)cc(OC)c1OC
ClassN,N'-disubstituted thiourea derivative
% Enzymatic Inhibition/Fold Change50.42% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000016

370

Physicochemical Properties