HSPMdb Accession NoHSPMDB000015
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound NameVER-155008
IUPAC Name4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
SMILESC1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
ClassDibenzyl-8-aminoadenosine analogue
% Enzymatic Inhibition/Fold Change43.03% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000015

VER-155008

Physicochemical Properties