HSPMdb Accession No | HSPMDB000014 |
PMID | 27155465 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | Az |
IUPAC Name | 4-[[2-[3,5-bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)imidazol-1-yl]methyl]benzamide |
SMILES | COC1=CC=C(C=C1)C2=C(N(C(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)CC4=CC=C(C=C4)C(=O)N)C5=CC=C(C=C5)OC |
Class | Imidazole derivative |
% Enzymatic Inhibition/Fold Change | 53.04% (at 200 uM) |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |