HSPMdb Accession NoHSPMDB000014
PMID27155465
TargetHsp70
HSP NameDnaK/DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound NameAz
IUPAC Name4-[[2-[3,5-bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)imidazol-1-yl]methyl]benzamide
SMILESCOC1=CC=C(C=C1)C2=C(N(C(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)CC4=CC=C(C=C4)C(=O)N)C5=CC=C(C=C5)OC
ClassImidazole derivative
% Enzymatic Inhibition/Fold Change53.04% (at 200 uM)
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000014

Az

Physicochemical Properties