HSPMdb Accession NoHSPMDB000013
PMID17904512
TargetHsp70
HSP NameDnaK/DnaJ/GrpE
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name116-9e
IUPAC Name6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1
ClassDihydropyrimidine derivative
IC50 (µM)Between 120 and 203
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000013

116-9e

Physicochemical Properties