HSPMdb Accession No | HSPMDB000013 |
PMID | 17904512 |
Target | Hsp70 |
HSP Name | DnaK/DnaJ/GrpE |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 116-9e |
IUPAC Name | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid |
SMILES | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 |
Class | Dihydropyrimidine derivative |
IC50 (µM) | Between 120 and 203 |
Type of Enzymatic Assay | ATPase assay |