HSPMdb Accession NoHSPMDB000011
PMID17904512
TargetHsp70
HSP NameDnaK/DnaJ/GrpE
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name116-4G
IUPAC Name6-{5-[(benzyloxy)carbonyl]-4-(4-cyclohexylphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1CCCCC1)C(=O)OCC1=CC=CC=C1
ClassDihydropyrimidine derivative
IC50 (µM)Between 120 and 201
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000011

116-4G

Physicochemical Properties