HSPMdb Accession NoHSPMDB000010
PMID17904512
TargetHsp70
HSP NameDnaK/DnaJ/GrpE
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name116-2F
IUPAC Namemethyl 4-(naphthalen-2-yl)-2-oxo-6-(phenoxymethyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESCOC(=O)C1=C(COC2=CC=CC=C2)NC(=O)NC1C1=CC2=C(C=CC=C2)C=C1
ClassDihydropyrimidine derivative
IC50 (µM)Between 120 and 200
Type of Enzymatic AssayATPase assay

Structure



HSPMDB000010

116-2F

Physicochemical Properties