| HSPMdb Accession No | HSPMDB000009 |
| PMID | 19793966 |
| Target | Hsp70 |
| HSP Name | Hsc70/ DnaJ |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Enzymatic activity | Activation of ATPase activity |
| Cellular activity | Increases total tau levels in cells overexpressing human tau protein |
| Compound Name | SW02 |
| IUPAC Name | ethyl 6-(4-bromophenyl)-3-(4-methoxy-4-oxobutyl)-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate |
| SMILES | CCOC(=O)C1=C(N(C(=O)NC1C2=CC=C(C=C2)Br)CCCC(=O)OC)C |
| Class | Dihydropyrimidine derivative |
| % Enzymatic Inhibition/Fold Change | 45% |
| EC50 (µM) | 120 to 150 |
| Type of Enzymatic Assay | ATPase assay |
| Cellular Model | HeLa |
| Disease | Alzheimers disease |
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