| HSPMdb Accession No | HSPMDB000008 |
| PMID | 19793966 |
| Target | Hsp70 |
| HSP Name | Hsc70/ DnaJ |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Enzymatic activity | Activation of ATPase activity |
| Cellular activity | Increases total tau levels in cells overexpressing human tau protein |
| Compound Name | 115-7c |
| IUPAC Name | 4-{5-[(benzyloxy)carbonyl]-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}butanoic acid |
| SMILES | CC1=C(C(NC(=O)N1CCCC(O)=O)C1=C(Cl)C=C(Cl)C=C1)C(=O)OCC1=CC=CC=C1 |
| Class | Dihydropyrimidine derivative |
| % Enzymatic Inhibition/Fold Change | 45% |
| EC50 (µM) | 120 to 150 |
| Type of Enzymatic Assay | ATPase assay |
| Cellular Model | HeLa |
| Disease | Alzheimers disease |
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