HSPMdb Accession NoHSPMDB000007
PMID19793966
TargetHsp70
HSP NameHsc70/ DnaJ
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityInhibition of ATPase activity
Compound NameMyricetin (MY)
IUPAC Name3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
SMILESC1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
ClassDihydropyrimidine derivative
% Enzymatic Inhibition/Fold Change> 80%
IC50 (µM)12
Type of Enzymatic AssayATPase assay
DiseaseAlzheimers disease

Structure



HSPMDB000007

Myricetin (MY)

Physicochemical Properties