| HSPMdb Accession No | HSPMDB000005 |
| PMID | 19793966 |
| Target | Hsp70 |
| HSP Name | Hsc70/ DnaJ |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Enzymatic activity | Inhibition of ATPase activity |
| Cellular activity | Decreases total tau levels in cells overexpressing human tau protein |
| Compound Name | Methylene blue (MB) |
| IUPAC Name | [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride |
| SMILES | CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-] |
| Class | Dihydropyrimidine derivative |
| % Enzymatic Inhibition/Fold Change | > 80% |
| IC50 (µM) | 83 |
| Type of Enzymatic Assay | ATPase assay |
| Cellular Model | HeLa |
| Disease | Alzheimers disease |
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