| HSPMdb Accession No | HSPMDB000004 |
| PMID | 16982771 |
| Target | Hsp70 |
| HSP Name | GRP78 |
| Organism | Human |
| Localization | Endoplasmic Reticulum |
| Enzymatic activity | Inhibition of ATPase activity |
| Compound Name | (-)-epigallocatechin (EGC) |
| IUPAC Name | (2~{R},3~{R})-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2~{H}-chromene-3,5,7-triol |
| SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O |
| Class | Polyphenol |
| % Enzymatic Inhibition/Fold Change | 58% inhibition at 10 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | ATPase assay |
| Disease | Cancer |
Loading Please Wait ...