HSPMdb Accession No | HSPMDB000002 |
PMID | 16982771 |
Target | Hsp70 |
HSP Name | GRP78 |
Organism | Human |
Localization | Endoplasmic Reticulum |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | (-)-epicatechin (EC) |
IUPAC Name | (2~{R},3~{R})-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2~{H}-chromene-3,5,7-triol |
SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O |
Class | Polyphenol |
% Enzymatic Inhibition/Fold Change | 38% inhibition at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |
Disease | Cancer |