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Record - 1 of 3   [TOP]
Compound IDNVIC0070
Compound Structure
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Inhibitor7-octyl-indolactam
PubChem ID 45934410
Drug Bank ID
ChemSpider ID 57263232
SMILESCCCCCCCCC1=C2CC(NC(=O)C(N(C3=CC=CC(=C23)N1)C)C(C)C)CO
Molecular Weight (in g/mol)413.606
TargetActivates PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of viral replication
IC50 (in nM)306820
EC50 (in nM)
H-bond Acceptor5
H-bond Donor3
No. of Rotatable Bond Count9
XLogP5.62
PSA68.36
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
Curatorkanikatuteja@gmail.com

                  
Record - 2 of 3   [TOP]
Compound IDNVIC0072
Compound Structure
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InhibitorOleic Acid
PubChem ID 445639
Drug Bank ID
ChemSpider ID 393217
SMILESCCCCCCCCC=CCCCCCCCC(=O)O
Molecular Weight (in g/mol)282.468
TargetActivates PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of viral replication
IC50 (in nM)1848200
EC50 (in nM)
H-bond Acceptor2
H-bond Donor1
No. of Rotatable Bond Count15
XLogP8.19
PSA37.30
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
Curatorkanikatuteja@gmail.com

                  
Record - 3 of 3   [TOP]
Compound IDNVIC0074
Compound Structure
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InhibitorPMA(Phorbol 12-myristate 13-acetate)
PubChem ID 27924
Drug Bank ID
ChemSpider ID 25977
SMILESCCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
Molecular Weight (in g/mol)616.825
TargetActivates PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of viral replication
IC50 (in nM)372120
EC50 (in nM)
H-bond Acceptor8
H-bond Donor3
No. of Rotatable Bond Count17
XLogP6.51
PSA130.36
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
Curatorkanikatuteja@gmail.com