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Compound IDNVIC0048
Compound Structure
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InhibitorChloroquine
PubChem ID 2719
Drug Bank IDDB00608
ChemSpider ID 2618
SMILESCCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
Molecular Weight (in g/mol)319.877
TargetCathepsin L
Assay TypeEfficay studies in disease animal model
Assay DescriptionDaily clinical observations
Assay SourceSigma Aldrich, NSW, Australia
Cell TypeFerret model
OutcomePreventing or moderating infection
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor3
H-bond Donor1
No. of Rotatable Bond Count8
XLogP4.14
PSA28.16
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772715/
PubMed ID [Source Literature] 19759137
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