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Record - 1 of 5   [TOP]
Compound IDNVIC0019
Compound Structure
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InhibitorRibavirin
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207
TargetRNA replication
Assay TypeDose-response assay
Assay DescriptionNon-linear regression analysis
Assay SourceValeant
Cell TypeHeLa cells
OutcomeReduce the spread and infection of NiV
IC50 (in nM)4180
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888097/
PubMed ID [Source Literature] 19889926
Curatornishisharmacool14@gmail.com

                  
Record - 2 of 5   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207
TargetReplication
Assay TypeBSL4 HTS assay
Assay DescriptionHRP-chemiluminescent
Assay Source
Cell TypeVero cells
OutcomeVirus inhibition
IC50 (in nM)
EC50 (in nM)3356
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
PubMed ID [Source Literature] 18313148
Curatorkanikatuteja@gmail.com

                  
Record - 3 of 5   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207
TargetReplication
Assay TypeBSL2 HTS assay
Assay DescriptionFluorescent immunodetection
Assay Source
Cell TypeVero cells
OutcomeVirus inhibition
IC50 (in nM)
EC50 (in nM)6041
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
PubMed ID [Source Literature] 18313148
Curatorpriyankapaul008@gmail.com

                  
Record - 4 of 5   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207
TargetReplication
Assay TypeCPE reduction assay
Assay DescriptionCPE Assay
Assay Source
Cell TypeVero E6 cells
OutcomeInhibit replication
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
PubMed ID [Source Literature] 16641448
Curatorkanikatuteja@gmail.com

                  
Record - 5 of 5   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207
TargetCrossing of the blood-brain barrier
Assay TypeStudy population
Assay DescriptionFollow-up of pateints
Assay Source
Cell Type
OutcomeReduction in mortality
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pubmed/11409437
PubMed ID [Source Literature] 11409437
Curatorkanikatuteja@gmail.com