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Compound IDNVIC0066
Compound Structure
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InhibitorAmiloride
PubChem ID 16231
Drug Bank ID
ChemSpider ID 15403
SMILESC1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
Molecular Weight (in g/mol)229.628
TargetInhibitor of sodium channels
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeSodium channel blockage
IC50 (in nM)656470
EC50 (in nM)
H-bond Acceptor6
H-bond Donor4
No. of Rotatable Bond Count2
XLogP-1.1
PSA159.29
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
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