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Compound IDNVIC0074
Compound Structure
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InhibitorPMA(Phorbol 12-myristate 13-acetate)
PubChem ID 27924
Drug Bank ID
ChemSpider ID 25977
SMILESCCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
Molecular Weight (in g/mol)616.825
TargetActivates PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of viral replication
IC50 (in nM)372120
EC50 (in nM)
H-bond Acceptor8
H-bond Donor3
No. of Rotatable Bond Count17
XLogP6.51
PSA130.36
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
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